Gene information
Official symbol KCNN4
Official full name potassium calcium-activated channel subfamily N member 4
Gene type protein-coding gene
Chromosome19q13.31
Alias symbolKCa3.1; hSK4; hKCa4; hIKCa1; IK
Gene familyPotassium calcium-activated channels
Resources
Entrez Gene 3783
HGNC HGNC:6293
Ensembl ENSG00000104783
Vega OTTHUMG00000182779
UCSC uc002oxl.3
GO terms: 62 records
GO Description Category LogP Number of genes Detail
GO:0005227 calcium activated cation channel activity GO Molecular Functions -2.46582511 5 More
GO:0005261 cation channel activity GO Molecular Functions -1.68739377 23 More
GO:0005267 potassium channel activity GO Molecular Functions -1.81540720 5 More
GO:0006813 potassium ion transport GO Biological Processes -2.38043550 7 More
GO:0006816 calcium ion transport GO Biological Processes -5.55009887 27 More
GO:0006869 lipid transport GO Biological Processes -16.6388990 29 More
GO:0007586 digestion GO Biological Processes -7.00342423 19 More
GO:0007589 body fluid secretion GO Biological Processes -11.5155091 20 More
GO:0008361 regulation of cell size GO Biological Processes -4.6524989 21 More
GO:0010876 lipid localization GO Biological Processes -20.1994935 34 More
GO:0010959 regulation of metal ion transport GO Biological Processes -23.6318171 71 More
GO:0015079 potassium ion transmembrane transporter activity GO Molecular Functions -1.41249432 5 More
GO:0015748 organophosphate ester transport GO Biological Processes -5.98331847 11 More
GO:0015914 phospholipid transport GO Biological Processes -7.60367088 11 More
GO:0019725 cellular homeostasis GO Biological Processes -21.1508273 85 More
GO:0019902 phosphatase binding GO Molecular Functions -2.86314983 18 More
GO:0019903 protein phosphatase binding GO Molecular Functions -3.28869574 16 More
GO:0022600 digestive system process GO Biological Processes -8.16734280 17 More
GO:0030001 metal ion transport GO Biological Processes -7.54203733 26 More
GO:0032535 regulation of cellular component size GO Biological Processes -4.60941253 33 More
GO:0032941 secretion by tissue GO Biological Processes -4.96271284 7 More
GO:0034204 lipid translocation GO Biological Processes -2.41427787 4 More
GO:0034702 ion channel complex GO Cellular Components -2.54472403 10 More
GO:0034703 cation channel complex GO Cellular Components -2.87762227 9 More
GO:0034705 potassium channel complex GO Cellular Components -2.39849900 5 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034764 positive regulation of transmembrane transport GO Biological Processes -18.2616571 46 More
GO:0034765 regulation of ion transmembrane transport GO Biological Processes -18.4305966 71 More
GO:0034767 positive regulation of ion transmembrane transport GO Biological Processes -11.2867591 18 More
GO:0042391 regulation of membrane potential GO Biological Processes -15.0641346 59 More
GO:0043025 neuronal cell body GO Cellular Components -9.18558636 52 More
GO:0043266 regulation of potassium ion transport GO Biological Processes -7.37974754 20 More
GO:0043268 positive regulation of potassium ion transport GO Biological Processes -3.46605627 5 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0043270 positive regulation of ion transport GO Biological Processes -23.5832054 34 More
GO:0044297 cell body GO Cellular Components -11.7206640 62 More
GO:0045332 phospholipid translocation GO Biological Processes -1.69110428 3 More
GO:0046873 metal ion transmembrane transporter activity GO Molecular Functions -1.47457965 10 More
GO:0046903 secretion GO Biological Processes -18.5147167 70 More
GO:0050708 regulation of protein secretion GO Biological Processes -30.3716714 63 More
GO:0050714 positive regulation of protein secretion GO Biological Processes -15.7339081 32 More
GO:0050856 regulation of T cell receptor signaling pathway GO Biological Processes -1.81572919 3 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051047 positive regulation of secretion GO Biological Processes -32.2282376 71 More
GO:0051222 positive regulation of protein transport GO Biological Processes -13.8994291 46 More
GO:0051223 regulation of protein transport GO Biological Processes -25.2801266 81 More
GO:0070201 regulation of establishment of protein localization GO Biological Processes -24.4831554 82 More
GO:0071805 potassium ion transmembrane transport GO Biological Processes -1.38276528 5 More
GO:0090066 regulation of anatomical structure size GO Biological Processes -32.7608623 52 More
GO:0097035 regulation of membrane lipid distribution GO Biological Processes -2.19985109 4 More
GO:0098655 cation transmembrane transport GO Biological Processes -3.98966777 20 More
GO:0098660 inorganic ion transmembrane transport GO Biological Processes -4.47276690 21 More
GO:0098662 inorganic cation transmembrane transport GO Biological Processes -4.65654157 20 More
GO:0098797 plasma membrane protein complex GO Cellular Components -14.6387951 39 More
GO:1901381 positive regulation of potassium ion transmembrane transport GO Biological Processes -1.81572919 3 More
GO:1902495 transmembrane transporter complex GO Cellular Components -2.24412383 11 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
GO:1903532 positive regulation of secretion by cell GO Biological Processes -27.9542102 63 More
GO:1903829 positive regulation of protein localization GO Biological Processes -12.9651258 57 More
GO:1904062 regulation of cation transmembrane transport GO Biological Processes -18.6629834 61 More
GO:1904064 positive regulation of cation transmembrane transport GO Biological Processes -10.8655330 17 More
GO:1904951 positive regulation of establishment of protein localization GO Biological Processes -13.0308630 46 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa04929 GnRH secretion KEGG Pathway -3.00923941 5 More
Drug-Gene interaction
view
Related drugs: 2 records
Drug name Interaction type Source PMID View
chlorzoxazone activator ChemblInteractionsTTD view
senicapoc blocker ChemblInteractionsTTD view
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
NM_002250.3:c.[820-60G>A;1049+78T>C;1120-487A>G] genomics myocardial infarction[diagnosis] myocardial infarction Yamaguchi M et al. Med Sci Monit. 2009
NM_002250.3:c.820-60G>A genomics myocardial infarction[diagnosis] myocardial infarction Yamaguchi M et al. Med Sci Monit. 2009
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